KRT19 Antibody Cocktail / Cytokeratin 19

• Description:

  This mAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

• UniProt:

  P08727

• Host:

  Mouse

• Immunogen:

  MCF-7 cells (A53-B/A2) and human mammary epithelial organoids (BA17) were used as the immunogen for this Cytokeratin 19 antibody cocktail.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ + IgG2a λ

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

• Reconstitution:

  Store the Cytokeratin 19 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This Cytokeratin 19 antibody cocktail is available for research use only.

• CAS Number:

  9007-83-4