CA19-9 Antibody

CAT: 0800-V3076SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V3076SAF-100UGSize:100 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This mAb is superb for staining of formalin-fixed, paraffin-embedded tissues.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT (1), Prediluted IHC only format: incubate for 30 min at RT (2)
UniProt
Not Known
Host
Mouse
Reactivity
Human
Immunogen
Precipitin lines obtained after immuno-diffusion using mAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le) were used as the immunogen for the CA19-9 antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
SPM588
Applications
IHC-P
Purity
PEG precipitation
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the CA19-9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CA19-9 antibody is available for research use only.
Storage Conditions
Store the CA19-9 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with CA19-9 antibody (SPM588) .

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