MVP Antibody / Major Vault Protein

MVP Antibody / Major Vault Protein

• Description: MVP is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
• CAS Number: 9007-83-4
• UniProt: Q14764
• Host: Mouse
• Immunogen: Proteins precipitated from human breast cancer MCF-7 cells were used as the immunogen for the Major Vault Protein antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: IHC-P
• Format: Purified
• Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Reconstitution: Store the Major Vault Protein antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This Major Vault Protein antibody is available for research use only.