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Emmprin Antibody

CAT: 0800-V2875-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V2875-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL
UniProt
P35613
Host
Mouse
Reactivity
Human
Immunogen
Native human leukocytes were used as the immunogen for the Emmprin antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
CB43
Applications
FACS, IF
Purity
PEG precipitation
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Emmprin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Emmprin antibody is available for research use only.
Storage Conditions
Store the Emmprin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Emmprin antibody should be determined by the researcher.
Location
Cell surface

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