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B2M Antibody / Beta-2 Microglobulin

CAT: 0800-V2801-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V2801-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serum Beta-2 Microglobulin (B2M) levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 1-2 µg/mL, Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
P61769
Host
Mouse
Reactivity
Human
Immunogen
Full length recombinant human protein was used as the immunogen for the B2M antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM617
Applications
IHC-P, WB, FACS, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the B2M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This B2M antibody is available for research use only.
Storage Conditions
Store the B2M antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of permeabilized human HeLa cells with B2M antibody (clone SPM617) .

UniProtKB · P61769

Beta-2-microglobulin

B2MG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61769
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
B2M
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
P01884, Q540F8, Q6IAT8, Q9UCK0, Q9UD48, Q9UDF4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

AmyloidMHC ISecreted

Disease

AmyloidosisDisease variant

PTM

Disulfide bondGlycationGlycoproteinPyrrolidone carboxylic acid

Biological process

Immunity

Domain

Immunoglobulin domainSignal
Product Datasheet
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