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SM-MHC Antibody

CAT: 0800-V2750SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V2750SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SM-MHC, or Myosin-11, is a smooth muscle myosin belonging to the myosin heavy chain family. Myosin-11 is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It is a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. [Wiki]
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P35749
Host
Mouse
Reactivity
Human, Rat
Immunogen
Human uterus extract was used as the immunogen for the SM-MHC antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ID8
Applications
FACS, IF, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the SM-MHC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This SM-MHC antibody is available for research use only.
Storage Conditions
Store the SM-MHC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human Leiomyosarcoma stained with SM-MHC antibody (ID8) .

UniProtKB · P35749

Myosin-11

MYH11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35749
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYH11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D2JYH7, O00396, O94944, P78422, Q3MIV8, Q3MNF0, Q3MNF1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin-bindingCalmodulin-bindingMotor proteinMuscle proteinMyosin

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Disease

Aortic aneurysmDisease variantProto-oncogene

Ligand

ATP-bindingNucleotide-binding

Domain

Coiled coil

PTM

MethylationPhosphoprotein

Cellular component

Thick filament

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