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SM-MHC Antibody

CAT: 0800-V2750IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V2750IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SM-MHC, or Myosin-11, is a smooth muscle myosin belonging to the myosin heavy chain family. Myosin-11 is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It is a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. [Wiki]
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P35749
Host
Mouse
Reactivity
Human, Rat
Immunogen
Human uterus extract was used as the immunogen for the SM-MHC antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ID8
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the SM-MHC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This SM-MHC antibody is available for research use only.
Storage Conditions
Store the SM-MHC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human Leiomyosarcoma stained with SM-MHC antibody (ID8) .

UniProtKB · P35749

Myosin-11

MYH11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35749
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYH11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D2JYH7, O00396, O94944, P78422, Q3MIV8, Q3MNF0, Q3MNF1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin-bindingCalmodulin-bindingMotor proteinMuscle proteinMyosin

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Disease

Aortic aneurysmDisease variantProto-oncogene

Ligand

ATP-bindingNucleotide-binding

Domain

Coiled coil

PTM

MethylationPhosphoprotein

Cellular component

Thick filament

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