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Fibronectin Antibody

CAT: 0800-V2503IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V2503IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Epitope of this mAb is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This mAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P02751
Host
Mouse
Reactivity
Human
Immunogen
High molecular weight proteins secreted by cultivated human fibroblasts were used as the immunogen for the Fibronectin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
568
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the Fibronectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Fibronectin antibody is available for research use only.
Storage Conditions
Store the Fibronectin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Connective tissue matrix
Image Legend
IHC: Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with Fibronectin antibody (clone 568) .

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