Semaphorin-4D Antibody / SEMA4D

• Description:

  Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

• UniProt:

  Q92854

• Host:

  Mouse

• Immunogen:

  PHA stimulated human peripheral blood lymphocytes were used as the immunogen for the Semaphorin-4D antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgM κ

• Applications:

  FACS, IF

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

• Reconstitution:

  Store the Semaphorin-4D antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This Semaphorin-4D antibody is available for research use only.

• CAS Number:

  9007-83-4