CD98 Antibody / SLC3A2

• Description:

  CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

• Specifications:

  Comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs, Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  The Molt-13 T cell line was used as the immunogen for this CD98 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  UM7F8

• Applications:

  Functional studies, FACS, IF

• Purity:

  Protein G purified CD98 antibody

• Format:

  Purified

• Buffer:

  1X PBS, pH 7.4

• Reconstitution:

  Store the CD98 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This CD98 antibody is available for research use only.

• Storage Conditions:

  Store the CD98 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

• Applications Notes:

  The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD98 antibody to be titered up or down for optimal performance.

• CAS Number:

  9007-83-4

• Location:

  Cell surface, cytoplasmic

• Image Legend:

  SDS-PAGE Analysis of Purified, BSA-Free CD98 Antibody (clone UM7F8) . Confirmation of Integrity and Purity of the Antibody.