RegisterLogin

CD33 Antibody

CAT: 0800-V2060-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V2060-100UGSize:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
This antibody recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505) . CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM) -containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/10^6 cells
Host
Mouse
Reactivity
Human
Immunogen
Human AML cells were used as the immunogen for this CD33 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
WM53
Applications
FACS
Purity
Protein G purified monoclonal antibody
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CD33 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD33 antibody is available for research use only.
Storage Conditions
Store the CD33 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD33 antibody to be titered up or down for optimal performance.1. Not suitable for use in FFPE IHC testing.
Location
Cell surface

Related Products

CatalogName
V4637-100UGSIGLEC3 Antibody / CD33
V4637SAF-100UGSIGLEC3 Antibody / CD33
V4637-20UGSIGLEC3 Antibody / CD33
V5822SAF-100UGRecombinant SIGLEC3 Antibody / Sialic acid-binding Ig-like lectin 3 / CD33
V5822-20UGRecombinant SIGLEC3 Antibody / Sialic acid-binding Ig-like lectin 3 / CD33
V5822-100UGRecombinant SIGLEC3 Antibody / Sialic acid-binding Ig-like lectin 3 / CD33
V2380SAF-100UGCD3 Antibody / CD3e
V2380-20UGCD3 Antibody / CD3e
V2380-100UGCD3 Antibody / CD3e
RQ5046CD3D Antibody / CD3 delta

Alternative Products

CatalogName
MBS7125256-01CD33 Antibody

Popular Products