CD147 Antibody

• Description :

  This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

• Specifications :

  The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Human T cell line Molt-13 was used as the immunogen for this CD147 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG1 k

• Clone :

  8D6

• Applications :

  IHC-P

• Purity :

  Protein G purified CD147 antibody

• Format :

  Purified

• Buffer :

  1X PBS, pH 7.4

• Reconstitution :

  Store the CD147 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations :

  This CD147 antibody is available for research use only.

• Storage Conditions :

  Store the CD147 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation :

  Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

• CAS Number :

  9007-83-4

• Location :

  Cell surface, cytoplasmic

• Image Legend :

  IHC testing of FFPE human renal cell carcinoma with CD147 antibody (clone 8D6) .