Products for Research Use Only

Cd27 Antibody

CAT: 0800-RQ6837Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6837Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD27 is a member of the tumor necrosis factor receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. And this receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P41272
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant mouse protein (amino acids P24-F187) was used as the immunogen for the Cd27 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Cd27 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cd27 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cd27 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Cd27 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE rat spleen tissue with Cd27 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.