Products for Research Use Only

Sentrin-specific protease 1 Antibody / SENP1

CAT: 0800-RQ6752Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6752Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sentrin-specific protease 1 is a protein that in human is encoded by the SENP1 gene. This gene is mapped to 12q13.11. This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
Q9P0U3
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein (amino acids N19-P619) was used as the immunogen for the Sentrin-specific protease 1 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
5F4
Applications
WB, FACS
Purity
Affinity purified
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Sentrin-specific protease 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Sentrin-specific protease 1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Sentrin-specific protease 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Sentrin-specific protease 1 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human K562 cells with Sentrin-specific protease 1 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Sentrin-specific protease 1 antibody.

UniProtKB · Q9P0U3

Sentrin-specific protease 1

SENP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9P0U3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SENP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.22.-
Processing
—
Secondary accessions
A8K7P5, Q86XC8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

HydrolaseProteaseThiol protease

PTM

Phosphoprotein

Biological process

Ubl conjugation pathway