Prothrombin Antibody

CAT: 0800-RQ6744Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ6744Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. This gene for human prothrombin (F2) was assigned to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1) . Thrombin also inhibits coagulation by activating protein C.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
P00734
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein (amino acids Y97-R124) was used as the immunogen for the Prothrombin antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
4G13G9
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Prothrombin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Prothrombin antibody is available for research use only.
Storage Conditions
After reconstitution, the Prothrombin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Prothrombin antibody should be determined by the researcher.
Location
Secreted
Image Legend
IHC staining of FFPE human ovarian cancer tissue with Prothrombin antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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