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PDLIM7 Antibody

CAT: 0800-RQ6669Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6669Size:100 µg
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Description
PDZ and LIM domain protein 7 is a protein that in humans is encoded by the PDLIM7 gene. The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9NR12
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids N275-V457) was used as the immunogen for the PDLIM7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the PDLIM7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PDLIM7 antibody is available for research use only.
Storage Conditions
After reconstitution, the PDLIM7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PDLIM7 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human gall bladder adenosquamous carcinoma tissue with PDLIM7 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · Q9NR12

PDZ and LIM domain protein 7

PDLI7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NR12
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PDLIM7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoskeleton

Molecular function

Developmental protein

Biological process

DifferentiationOsteogenesis

Domain

LIM domainRepeat

Ligand

Metal-bindingZinc

PTM

MethylationPhosphoprotein

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