RRP4 Antibody / EXOSC2

CAT: 0800-RQ6623Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ6623Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Exosome component 2, also known as Exosome complex component RRP4 and EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snoRNA and snRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. EXOSC2 is a non-catalytic component of the RNA exosome complex that has 3'->5' exoribonuclease activity and involves in a multitude of cellular RNA processing and degradation events.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q13868
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids R62-G293) was used as the immunogen for the RRP4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the RRP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RRP4 antibody is available for research use only.
Storage Conditions
After reconstitution, the RRP4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RRP4 antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear
Image Legend
IHC staining of FFPE human appendiceal adenocarcinoma tissue with RRP4 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Product Datasheet
Loading...

Related Products

CatalogName
R35793-100UGEXOSC9 Antibody
RQ6624EXOSC8 Antibody
RQ4644DIS3 Antibody / RRP44
F53923-0.2MLRPLP1 Antibody / RRP1
F53923-0.05MLRPLP1 Antibody / RRP1
R33556-100UGEXOC7 Antibody
FY12008EXOC2 Antibody / Exocyst complex component 2
FY13219DIS3 Antibody / Exosome complex exonuclease RRP44
RQ7581RRP8 Antibody / Ribosomal RNA-processing protein 8
RQ7866NNP1 Antibody / Novel nuclear protein 1 / RRP1

Alternative Products

CatalogName
E12-848RRP4/EXOSC2 Rabbit Polyclonal Antibody
MBS1755738-01Anti-RRP4/EXOSC2 Antibody Picoband
A10119-1Anti-RRP4/EXOSC2 Antibody Picoband®
TA343807RRP4 (EXOSC2) Rabbit Polyclonal Antibody
abx112411Exosome Complex Component RRP4 (EXOSC2) Antibody
A10119-1-Fluoro488Anti-RRP4/EXOSC2 Antibody Picoband® Fluoro488 Conjugated
A10119-1-FITCAnti-RRP4/EXOSC2 Antibody Picoband®, FITC Conjugate
A10119-1-HRPAnti-RRP4/EXOSC2 Antibody Picoband®, HRP Conjugate
A10119-1-Dylight550Anti-RRP4/EXOSC2 Antibody Picoband®, Dylight550 Conjugate
A10119-1-PEAnti-RRP4/EXOSC2 Antibody Picoband®, PE Conjugate

Popular Products