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LACTB Antibody / MRPL56

CAT: 0800-RQ6567Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6567Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Serine beta-lactamase-like protein LACTB, mitochondrial is an enzyme that in humans is encoded by the LACTB gene. This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P83111
Host
Rabbit
Reactivity
Human
Immunogen
An E. coli-derived human protein (amino acids E141-K543) was used as the immunogen for the LACTB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the LACTB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This LACTB antibody is available for research use only.
Storage Conditions
After reconstitution, the LACTB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LACTB antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human liver cancer tissue with LACTB antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · P83111

Serine beta-lactamase-like protein LACTB, mitochondrial

LACTB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P83111
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LACTB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.-.-
Processing
Precursor
Secondary accessions
P83096
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Molecular function

HydrolaseProtease

Biological process

Lipid metabolism

Cellular component

Mitochondrion

Domain

Transit peptide

Disease

Tumor suppressor

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