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RALBP1 Antibody

CAT: 0800-RQ6536Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6536Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene. Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS, which in turn is activated by RAS. RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL. RALBP1 is also the dominant transporter of lipid peroxidation-derived glutathione conjugates and participates in several mitotic events, including inactivation of endocytosis and separation and polar movement of centrioles and appropriate distribution of mitochondria to daughter cells following mitosis.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
Q15311
Host
Mouse
Reactivity
Human
Immunogen
An E. coli-derived human protein (amino acids K239-Q506) was used as the immunogen for the RALBP1 antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
2E11.
Applications
WB, FACS
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the RALBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RALBP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the RALBP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the RALBP1 antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear, cell membrane
Image Legend
Flow cytometry testing of human U-87 MG cells with RALBP1 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= RALBP1 antibody.

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