Proteasome subunit beta type-6 Antibody / PSMB6

Proteasome subunit beta type-6 Antibody / PSMB6

• Description: Proteasome subunit beta type-6 also known as 20S proteasome subunit beta-1 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB6 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• CAS Number: 9007-83-4
• UniProt: P28072
• Host: Rabbit
• Immunogen: An E. coli-derived human protein (amino acids A50-D201) was used as the immunogen for the Proteasome subunit beta type-6 antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, FACS, Direct ELISA
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the Proteasome subunit beta type-6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This Proteasome subunit beta type-6 antibody is available for research use only.