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MAVS Antibody / IPS-1

CAT: 0800-RQ6496Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6496Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL
UniProt
Q7Z434
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids DEVASVYQSYQPRTSDRPPDPLE from the human protein were used as the immunogen for the MAVS antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the MAVS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MAVS antibody is available for research use only.
Storage Conditions
After reconstitution, the MAVS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MAVS antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human Caco-2 cells with MAVS antibody (green) and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · Q7Z434

Mitochondrial antiviral-signaling protein

MAVS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q7Z434
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAVS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MAVS
EC number
—
Processing
—
Secondary accessions
A8K6X0, B2BD33, B2BD34, F5H6C8, M1P2Z0, Q2HWT5, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseHost-virus interactionImmunityInnate immunity

Cellular component

MembraneMitochondrionMitochondrion outer membranePeroxisome

Domain

TransmembraneTransmembrane helix

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CatalogName
NBP1-76768CL1Rabbit Polyclonal MAVS Antibody [CoraFluor 1]
NBP2-80052Mouse Monoclonal MAVS Antibody (Adri-1)
NBP2-80052PEMouse Monoclonal MAVS Antibody (Adri-1) [PE]
NBP2-80052PCPMouse Monoclonal MAVS Antibody (Adri-1) [PerCP]
NBP2-80052FMouse Monoclonal MAVS Antibody (Adri-1) [FITC]
NBP2-80052HMouse Monoclonal MAVS Antibody (Adri-1) [HRP]
NBP2-80052CL1Mouse Monoclonal MAVS Antibody (Adri-1) [CoraFluor 1]
NBP2-80052BMouse Monoclonal MAVS Antibody (Adri-1) [Biotin]
NBP2-72593CL1Mouse Monoclonal MAVS Antibody (OTI9C4) [CoraFluor 1]
NBP2-80052APCMouse Monoclonal MAVS Antibody (Adri-1) [Allophycocyanin]

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