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Duox2 Antibody

CAT: 0800-RQ6472Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6472Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
B7ZWM4
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
An E. coli-derived mouse protein (amino acids A63-D403) was used as the immunogen for the Duox2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Duox2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Duox2 antibody is available for research use only.
Storage Conditions
After reconstitution, the Duox2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Duox2 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE mouse colon tissue with Duox2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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