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Raptor Antibody

CAT: 0800-RQ6395Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6395Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q8N122
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids R301-R358) was used as the immunogen for the Raptor antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, Direct ELISA
Purity
Antigen affinity purified
Format
Purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Raptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Raptor antibody is available for research use only.
Storage Conditions
After reconstitution, the Raptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Raptor antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HepG2, 2) HeLa, 3) MCF7, 4) HEK293, 5) A549, 6) rat brain and 7) mouse brain tissue lysate with Raptor antibody. Predicted molecular weight ~ 149 kDa.
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