SAMHD1 Antibody

• Description:

  SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

• Specifications:

  Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells

• UniProt:

  Q9Y3Z3

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant human protein (amino acids E37-M626) was used as the immunogen for the SAMHD1 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2b

• Clone:

  10H8

• Applications:

  WB, IHC-P, IF, FACS

• Purity:

  Antigen affinity purified

• Format:

  Purified

• Buffer:

  Lyophilized from 1X PBS with 2% Trehalose

• Reconstitution:

  After reconstitution, the SAMHD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This SAMHD1 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the SAMHD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Optimal dilution of the SAMHD1 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Nuclear

• Image Legend:

  IHC staining of FFPE human ovarian serous adenocarcinoma tissue with SAMHD1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.