UBR2 Antibody

• Description :

  E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene. It is mapped to 6p21.1. This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.

• Specifications :

  Western blot: 1-2 µg/mL

• UniProt :

  Q8IWV8

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  A human recombinant partial protein (amino acids Q10-A664) was used as the immunogen for the UBR2 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG2a

• Clone :

  2G11

• Applications :

  WB

• Purity :

  Affinity purified

• Format :

  Antigen affinity purified

• Buffer :

  Lyophilized from 1X PBS with 2% Trehalose

• Reconstitution :

  After reconstitution, the UBR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations :

  This UBR2 antibody is available for research use only.

• Storage Conditions :

  After reconstitution, the UBR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation :

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes :

  Optimal dilution of the UBR2 antibody should be determined by the researcher.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot testing of human 1) HEK293, 2) Jurkat and 3) K562 cell lysate with UBR2 antibody. Predicted molecular weight ~202 kDa.