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Tigit Antibody

CAT: 0800-RQ6213Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6213Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is an immune receptor present on some T cells and Natural Killer Cells (NK) . This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH) . The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P86176
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A mouse recombinant partial protein (amino acids T29-G249) was used as the immunogen for the Tigit antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.0125% sodium azide
Reconstitution
After reconstitution, the Tigit antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Tigit antibody is available for research use only.
Storage Conditions
After reconstitution, the Tigit antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Tigit antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE mouse spleen with Tigit antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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MBS9217285-01TIGIT Antibody

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