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NRXN3 Antibody

CAT: 0800-RQ6203Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6203Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neurexin 3 is a protein that in humans is encoded by the NRXN3 gene. This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9HDB5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A human recombinant partial protein (amino acids R294-P549) was used as the immunogen for the NRXN3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the NRXN3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NRXN3 antibody is available for research use only.
Storage Conditions
After reconstitution, the NRXN3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NRXN3 antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of human U-2 OS cells with NRXN3 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= NRXN3 antibody.

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