TIMM8A Antibody

CAT: 0800-RQ6157Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ6157Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Mitochondrial import inner membrane translocase subunit Tim8 A, also known as Deafness-dystonia peptide or protein is an enzyme that in humans is encoded by the TIMM8A gene. This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
O60220
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
A human recombinant partial protein (amino acids A14-D97) was used as the immunogen for the TIMM8A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the TIMM8A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TIMM8A antibody is available for research use only.
Storage Conditions
After reconstitution, the TIMM8A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TIMM8A antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human testicular cancer with TIMM8A antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Product Datasheet
Loading...

Related Products

CatalogName
FY12759TIMM8B Antibody / Tim8 B
RQ4949TIMM17A Antibody
R33215-100UGTIMM50 Antibody
F55074-0.05MLTIMM23 Antibody / Tim23
F55074-0.2MLTIMM23 Antibody / Tim23
FY12894TIMM9 Antibody / Tim9
FY12027TIMM44 Antibody / Translocase of inner mitochondrial membrane 44
FY13316TIMM50 Antibody / Translocase of inner mitochondrial membrane 50
FY12608TIMM22 Antibody / Translocase of inner mitochondrial membrane 22
FY13139TIMM10 Antibody / TIM10 / Mitochondrial import inner membrane translocase subunit Tim10

Alternative Products

CatalogName
23-916TIMM8A Antibody
STJ111853Anti-TIMM8A antibody
ANT-14737-100ugTIMM8A Polyclonal Antibody
MBS9455111-01TIMM8A Conjugated Antibody
pro-1818TIMM8A

Popular Products