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SLC25A19 Antibody

CAT: 0800-RQ6117Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ6117Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene. This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL
UniProt
Q9HC21
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids PFDVIKIRFQLQHERL from the human protein were used as the immunogen for the SLC25A19 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the SLC25A19 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SLC25A19 antibody is available for research use only.
Storage Conditions
After reconstitution, the SLC25A19 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SLC25A19 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HEK293, 2) PC-3 and 3) MCF7 lysate with SLC25A19 antibody. Predicted molecular weight ~41 kDa.

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