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CDR2 Antibody

CAT: 0800-RQ5966Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5966Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cerebellar degeneration-related protein 2 is a protein that in humans is encoded by the CDR2 gene. By a combination of study of rodent/human somatic cell hybrids and in situ hybridization, this gene is assigned to 16p13.1-p12. The onconeuronal cerebellar degeneration-related antigen Cdr2 is associated with paraneoplastic syndromes. Neoplastic expression of Cdr2 in ovary and breast tumors triggers an autoimmune response that suppresses tumor growth by developing tumor immunity, but culminates in cerebellar degeneration when Cdr2-specific immune cells recognize neuronal Cdr2.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry: 1-2 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q01850
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids M1-D441) was used as the immunogen for the CDR2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the CDR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CDR2 antibody is available for research use only.
Storage Conditions
After reconstitution, the CDR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CDR2 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human breast cancer with CDR2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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