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NFAT5 Antibody

CAT: 0800-RQ5900Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5900Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
O94916
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human protein (amino acids M1-D394) was used as the immunogen for the NFAT5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, IF, IHC-P, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the NFAT5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NFAT5 antibody is available for research use only.
Storage Conditions
After reconstitution, the NFAT5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NFAT5 antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of FFPE human bladder cancer tissue with NFAT5 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.

UniProtKB · O94916

Nuclear factor of activated T-cells 5

NFAT5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O94916
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NFAT5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
NF-AT5
EC number
—
Processing
—
Secondary accessions
A2RRB4, A6H8V5, E9PHR7, O95693, Q7LA65, Q969Q8, Q96QH3, Q9UN18
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageTranscriptionTranscription regulation
Product Datasheet
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