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MADCAM1 Antibody

CAT: 0800-RQ5894Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5894Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1), also known as MACAM1, is a protein that in humans is encoded by the MADCAM1 gene. By PCR-based analysis of somatic cell hybrids, this gene is mapped to chromosome 19. The protein encoded by this gene is an endothelil cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4 / beta7), L-selectin, and VLA-4 (alpha4 / beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.
CAS Number
9007-83-4
Specifications
Immunohistochemistry: 1-2 µg/mL
UniProt
Q13477
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids QEEEEEPQGDEDVLFRVTERWRL from the human protein were used as the immunogen for the MADCAM1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the MADCAM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MADCAM1 antibody is available for research use only.
Storage Conditions
After reconstitution, the MADCAM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MADCAM1 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human rectal cancer with MADCAM1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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MBS8500570-01MADCAM1 Antibody

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