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Cd63 Antibody / Lamp-3

CAT: 0800-RQ5804Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5804Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD63 antigen is a protein that in humans is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It is mapped to 12q13.2. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression.
CAS Number
9007-83-4
Specifications
Immunohistochemistry: 1-2 µg/mL
UniProt
P41731
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids AVAIAGYVFRDQVKSE from the mouse protein were used as the immunogen for the Cd63 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Cd63 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cd63 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cd63 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Cd63 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE mouse spleen with Cd63 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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