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Tuberin Antibody

CAT: 0800-RQ5616Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5616Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin is a protein that is in humans. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. This gene involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P49815
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant protein (amino acids H1611-V1807) was used as the immunogen for the Tuberin antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
6I3
Applications
WB
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Tuberin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Tuberin antibody is available for research use only.
Storage Conditions
After reconstitution, the Tuberin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Tuberin antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) HEK293 and 2) PC-3 cell lysate with Tuberin antibody. Expected molecular weight: 200~220 kDa.

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