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SUZ12 Antibody

CAT: 0800-RQ5598Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5598Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene. It is mapped to 17q11.2. This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
CAS Number
9007-83-4
Specifications
Western blot: 0.25-0.5 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Immunofluorescence: 5 µg/mL, Direct ELISA : 0.1-0.5 µg/mL
UniProt
Q15022
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A human recombinant protein (amino acids K72-K483) was used as the immunogen for the SUZ12 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the SUZ12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SUZ12 antibody is available for research use only.
Storage Conditions
After reconstitution, the SUZ12 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SUZ12 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human breast cancer with SUZ12 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.

UniProtKB · Q15022

Polycomb protein SUZ12

SUZ12_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15022
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SUZ12
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q96BD9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Chromatin regulatorRepressor

Coding sequence diversity

Chromosomal rearrangement

Disease

Disease variantIntellectual disabilityProto-oncogene

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger
Product Datasheet
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