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Radixin Antibody

CAT: 0800-RQ5597Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5597Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Radixin is a protein that in humans is encoded by the RDX gene. Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.25-0.5 µg/mL, Immunofluorescence: 2-4 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P35241
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids AKQAADQMKNQEQLAAELAEFTAKIALLEEAKK were used as the immunogen for the Radixin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF/ICC, FACS
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the Radixin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Radixin antibody is available for research use only.
Storage Conditions
After reconstitution, the Radixin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Radixin antibody should be determined by the researcher.
Image Legend
IF/ICC staining of FFPE human HeLa cells with Radixin antibody (green) at 2ug/ml and DAPI nuclear stain (blue) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · P35241

Radixin

RADI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35241
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RDX
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A7YIJ8, A7YIK0, A7YIK3, B7Z9U6, F5H1A7, Q86Y61
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin cappingActin-binding

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionCytoplasmCytoskeletonMembrane

Disease

DeafnessDisease variantNon-syndromic deafness

PTM

Phosphoprotein

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