FOXC1 Antibody

CAT: 0800-RQ5578Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ5578Size:100 µg
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Description
Forkhead box C1, also known as FOXC1, is a protein which in humans is encoded by the FOXC1 gene. It is mapped to 6p25.3. This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q12948
Host
Rabbit
Reactivity
Human
Immunogen
A human recombinant protein (amino acids T392-F554) was used as the immunogen for the FOXC1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the FOXC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This FOXC1 antibody is available for research use only.
Storage Conditions
After reconstitution, the FOXC1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the FOXC1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HEK293 cell lysate with FOXC1 antibody. Predicted molecular weight: ~57 kDa, routinely observed at up to 75 kDa.

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