PDHB Recombinant Antibody / Pyruvate Dehydrogenase E1 beta subunit

• Description:

  The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. [RefSeq]

• UniProt:

  P11177

• Host:

  Rabbit

• Immunogen:

  A synthetic peptide specific to human Pyruvate Dehydrogenase E1 beta subunit / PDHB was used as the immunogen for the PDHB antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Type:

  Recombinant

• Applications:

  WB

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the PDHB antibody at -20oC.

• Limitations:

  This PDHB antibody is available for research use only.

• CAS Number:

  9000-83-3