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Tau Antibody / MAPT

CAT: 0800-RQ5332Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ5332Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer's disease and Parkinson's disease are associated with tau proteins that have become defective and no longer stabilize microtubules properly. [Wiki]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P10636
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human Tau / MAPT was used as the immunogen for the Tau antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
GF-13
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Tau antibody at -20oC.
Limitations
This Tau antibody is available for research use only.
Storage Conditions
Store the Tau antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Tau antibody should be determined by the researcher.
Image Legend
Western blot testing of human SH-SY5Y cell lysate with Tau antibody. Expected molecular weight: 50-80 kDa.

UniProtKB · P10636

Microtubule-associated protein tau

TAU_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P10636
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAPT
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycationGlycoproteinIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseDisease variantNeurodegenerationParkinsonism

Cellular component

Cell membraneCell projectionCytoplasmCytoskeletonMembraneMicrotubuleSecreted

Domain

Repeat

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