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LONP1 Antibody

CAT: 0800-RQ5309Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ5309Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1gene. It is mapped to 19p13.3. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL, Immunofluorescence (FFPE) : 2-4 µg/mL, Flow cytometry: 1-3ug/million cells, Immunoprecipitation: 2ug per 500ug of lysate
UniProt
P36776
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids R137-A320 from the human protein were used as the immunogen for the LONP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, IP, Direct ELISA
Purity
Affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
Store the LONP1 antibody at -20oC.
Limitations
This LONP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the LONP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LONP1 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human rectal cancer with LONP1 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.

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MBS7129232-01LONP1 Antibody

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