P Glycoprotein Recombinant Antibody / MDR1 / ABCB1

P Glycoprotein Recombinant Antibody / MDR1 / ABCB1

• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [RefSeq]
• CAS Number: 9000-83-3
• UniProt: P08183
• Host: Rabbit
• Immunogen: A synthetic peptide specific to human P Glycoprotein / ABCB1 / MDR1 was used as the immunogen for the MDR1 antibody.
• Clonality: Monoclonal
• Isotype: IgG
• Type: Recombinant
• Applications: WB
• Format: Purified
• Buffer: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
• Reconstitution: Store the MDR1 antibody at -20oC.
• Limitations: This MDR1 antibody is available for research use only.