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Fyn Antibody

CAT: 0800-RQ5137Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ5137Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000, Immunofluorescence: 1:25-1:100
UniProt
P06241
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human Fyn was used as the immunogen for the Fyn antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BED-6
Type
Recombinant
Applications
WB, IF
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Fyn antibody at -20oC.
Limitations
This Fyn antibody is available for research use only.
Storage Conditions
Store the Fyn antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Fyn antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) mouse brain and 2) human HEK293 lysate with Fyn antibody. Predicted molecular weight ~59 kDa.

UniProtKB · P06241

Tyrosine-protein kinase Fyn

FYN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P06241
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FYN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
B5BU57, E1P557, H0UI48, Q16248, Q5R3A6, Q5R3A7, Q8N5D7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityHost-virus interactionImmunity

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingManganeseMetal-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembraneNucleus

Molecular function

Developmental proteinKinaseTransferaseTyrosine-protein kinase

PTM

LipoproteinMyristatePalmitatePhosphoprotein

Disease

Proto-oncogene

Domain

SH2 domainSH3 domain

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