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LCK Antibody

CAT: 0800-RQ5136Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ5136Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene is a member of the Src family of protein tyrosine kinases (PTKs) . The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
P06239
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human LCK was used as the immunogen for the LCK antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ADBE-12
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the LCK antibody at -20oC.
Limitations
This LCK antibody is available for research use only.
Storage Conditions
Store the LCK antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the LCK antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with LCK antibody. Predicted molecular weight ~58 kDa.

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