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PF4 Antibody / Platelet factor 4

CAT: 0800-RQ5014Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ5014Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P02776
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human PF4 was used as the immunogen for the PF4 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ACED-16
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the PF4 antibody at -20oC.
Limitations
This PF4 antibody is available for research use only.
Storage Conditions
Store the PF4 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the PF4 antibody should be determined by the researcher.
Image Legend
Western blot testing of human spleen lysate with PF4 antibody. Expected molecular weight: ~8/16/32 kDa (monomer/dimer/tetramer) .

UniProtKB · P02776

Platelet factor 4

PLF4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02776
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PF4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PF-4
EC number
—
Processing
Precursor
Secondary accessions
Q53X61, Q9UC64, Q9UC65
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Chemotaxis

Molecular function

CytokineHeparin-binding

PTM

Disulfide bondPhosphoprotein

Cellular component

Secreted

Domain

Signal

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