CPAMD8 Antibody

• Description:

  CPAMD8 belongs to the complement component-3 (C3) / alpha-2-macroglobulin (A2M) family of proteins, which are involved in innate immunity and damage control. The encoded protein is membrane-associated and proteolytically processed to generate two chains. Mutations in this gene cause a form of anterior segment dysgenesis, a developmental disorder of the eye. By genomic sequence analysis, the CPAMD8 gene is mapped to chromosome 19p13.3-p13.2.

• Specifications:

  Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

• UniProt:

  Q8IZJ3

• Host:

  Rabbit

• Reactivity:

  Human, Monkey

• Immunogen:

  Amino acids R58-D234 from the human protein were used as the immunogen for the CPAMD8 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB, IHC-P, Direct ELISA

• Purity:

  Antigen affinity purified

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

• Reconstitution:

  After reconstitution, the CPAMD8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This CPAMD8 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the CPAMD8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Optimal dilution of the CPAMD8 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic

• Image Legend:

  Western blot testing of human 1) placenta, 2) T-47D, 3) U-2 OS, 4) K562, 5) ThP-1 and 6) monkey COS-7 lysate with CPAMD8 antibody at 0.5ug/ml. Predicted molecular weight ~207 kDa.