TAF12 Antibody

CAT: 0800-RQ4927Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ4927Size:100 µg
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Description
Transcription initiation factor TFIID subunit 12 is a protein that in humans is encoded by the TAF12 gene. Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q16514
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids QIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQ from the human protein were used as the immunogen for the TAF12 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the TAF12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TAF12 antibody is available for research use only.
Storage Conditions
After reconstitution, the TAF12 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TAF12 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of human 1) placenta, 2) U-937, 3) K562 and 4) ThP-1 lysate with TAF12 antibody at 0.5ug/ml. Expected molecular weight ~21 kDa.
Product Datasheet
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