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NRAS Antibody

CAT: 0800-RQ4865Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4865Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. It has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in the gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:10000-1:20000
UniProt
P01111
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A synthetic peptide specific to human NRAS was used as the immunogen for the NRAS antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
DBC-14
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the NRAS antibody at -20oC.
Limitations
This NRAS antibody is available for research use only.
Storage Conditions
Store the NRAS antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the NRAS antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat C6 and 2) human Jurkat cell lysate with NRAS antibody. Predicted molecular weight ~21 kDa.

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