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SERPINA3 Antibody

CAT: 0800-RQ4851Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4851Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:1000
UniProt
P01011
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human SERPINA3 / alpha 1 Antichymotrypsin was used as the immunogen for the SERPINA3 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ADED-19
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the SERPINA3 antibody at -20oC.
Limitations
This SERPINA3 antibody is available for research use only.
Storage Conditions
Store the SERPINA3 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the SERPINA3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human plasma lysate with SERPINA3 antibody. Expected molecular weight: 47-65 kDa, depending on level of glycosylation.

UniProtKB · P01011

Alpha-1-antichymotrypsin

AACT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01011
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINA3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ACT
EC number
—
Processing
Precursor
Secondary accessions
B3KVQ7, Q13703, Q2TU87, Q2TU88, Q59GP9, Q6LBY8, Q6LDT7, Q6NSC9, Q8N177, Q96DW8, Q9UC47, Q9UNU9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Acute phase

Coding sequence diversity

Alternative splicing

PTM

Glycoprotein

Molecular function

Protease inhibitorSerine protease inhibitor

Cellular component

Secreted

Domain

Signal

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