Products for Research Use Only

SOD1 Antibody

CAT: 0800-RQ4835Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4835Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P00441
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human SOD1 was used as the immunogen for the SOD1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
AOEI-19
Type
Recombinant
Applications
WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the SOD1 antibody at -20oC.
Limitations
This SOD1 antibody is available for research use only.
Storage Conditions
Store the SOD1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the SOD1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human Jurkat cell lysate with SOD1 antibody. Predicted molecular weight ~16 kDa.

UniProtKB · P00441

Superoxide dismutase [Cu-Zn]

SODC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00441
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SOD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.15.1.1, 1.8.-.-
Processing
—
Secondary accessions
A6NHJ0, D3DSE4, Q16669, Q16711, Q16838, Q16839, Q16840, Q6NR85
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Disease

Amyotrophic lateral sclerosisDisease variantNeurodegeneration

Molecular function

AntioxidantOxidoreductase

Ligand

CopperMetal-bindingZinc

Cellular component

CytoplasmNucleus

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