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KDM1 / LSD1 Antibody

CAT: 0800-RQ4754Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ4754Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200
UniProt
O60341
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Lysine-specific histone demethylase 1A was used as the immunogen for the KDM1 / LSD1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
DID-11
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the KDM1 / LSD1 antibody at -20oC.
Limitations
This KDM1 / LSD1 antibody is available for research use only.
Storage Conditions
Store the KDM1 / LSD1 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the KDM1 / LSD1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of human HeLa lysate with KDM1 / LSD1 antibody. Predicted molecular weight ~110 kDa.

UniProtKB · O60341

Lysine-specific histone demethylase 1A

KDM1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60341
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDM1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.11.-, 1.14.11.65, 1.14.99.66
Processing
—
Secondary accessions
A8MWP9, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorDevelopmental proteinOxidoreductaseRepressor

Cellular component

ChromosomeNucleus

Domain

Coiled coil

Disease

Cushing syndromeDisease variant

Ligand

FADFlavoprotein

Biological process

TranscriptionTranscription regulation
Product Datasheet
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